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  • Dataset: Pharmacokinetic Study of Carbidopa

    This dataset comes from a study of 12 healthy males randomly assigned to a three-period crossover design, in which were given one of 3 doses of a drug. Blood samples were collected at specified time intervals, and data on plasma levels were collected. Questions from this study refer to the relationship between dosage and plasma levels. A text file version of the data is found in the relation link.

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  • Dataset: Organ Weight Study in Rats

    This dataset comes from a study of 90 rats given one of 3 doses of a drug. At sacrifice, data on body weight and the weights of various organs were collected. Questions from this study refer to the relationship between dosage and body and organ weight. A text file version of the data is found in the relation link.

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  • Dataset: Developmental Signs Testing in Rat Pups

    This dataset comes from a study of rats given one of 4 doses of a drug. The resulting pups were tested for developmental signs. Questions from this study refer to the relationship between dosage and developmental response. A text file version of the data is found in the relation link.

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  • Dataset: Blood Pressure Study

    This dataset comes from a study of diabetic patients randomly assigned to a two-period crossover design. Patients were given 1 of 2 drug sequences (EN, NE) in each period and blood pressure was recorded. Questions from this study refer to the ability of the drugs to lower blood pressure. A text file version of the data is found in the relation link.

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  • Dataset: Drug Interaction Study

    This dataset comes from a study of 8 healthy patients randomly assigned to a two-period crossover design. Patients were given 1 of 2 drug sequences and data on blood plasma levels wer recorded. Questions from this study refer how the drugs affect plasma levels. A text file version of the data is found in the relation link.

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  • Dataset: Bioequivalence Study II

    This dataset comes from a study of 26 healthy male subjects randomly assigned to a two-period crossover design. Patients were given either Drug A or Drug B, and data on plasma levels were collected. Questions from this study refer the similarity of the drugs. A text file version of the data is found in the relation link.

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  • Dataset: Method Comparison Study

    This dataset comes from a study of 48 hypertensive patients given one of 3 doses of one drug and one dose of another drug. Questions from this study refer to associations and relationships between the drugs. A text file version of the data is found in the relation link.

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  • Dataset: Combination Therapy Bioequivalence Study

    This dataset comes from a study of 16 healthy subjects randomly assigned to one of two treatment sequences in a two period crossover design. Treatments were from two different drug companies. Questions from this study refer to the similarities of the two treatments. A text file version of the data is found in the relation link.

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  • Dataset: Oral Teratogenic Study in Mice

    This dataset comes from a study of 100 female mice treated with one of 3 doses of a drug, and then impregnated by untreated males. The fetuses were examined for skeletal malformations. Questions from this study refer to the relationship between affected fetuses and dosage. A text file version of the data is found in the relation link.

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  • Dataset: Hexobarbital-Metabolizing Enzyme Induction Study in Mice

    This dataset comes from a study of 100 mice assigned randomly to one of five treatment groups of graded dosages of a drug. They were also given an injection of another drug, and sleeping times were recorded for each mouse. Questions from this study refer to the relationship between sleeping times and dosage. A text file version of the data is found in the relation link.

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