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  • This dataset comes from a study of 14 healthy subjects given one dose of a drug for seven days. Blood samples were taken before and after treatment, and plasma levels were recorded. Questions from this study refer to the increase in plasma level after treatment. A text file version of the data is found in the relation link.
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  • This dataset comes from two studies, one of 16 healthy young subjects and another of 14 healthy elderly subjects, each given a drug in two treatment periods. Blood samples were taken, and plasma levels were recorded. Questions from this study refer to whether age or gender affects plasma level. A text file version of the data is found in the relation link.
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  • This dataset comes from a study on 200 rats (100 of each gender) which were given one of 5 treatments, and then allowed to mate. At delivery, information on the pups was collected, and a sample of 8 pups (4 of each gender) was chosen from each litter. Body weights for these pups were recorded once a week for three weeks. Questions this study focused on refer to the safety of the treatments. A text file version of the data is found in the relation link.
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  • This dataset comes from a study on two treatment sequences (AB, BA) given to 14 healthy male volunteers randomly assigned to a two-period crossover design. Three pharmacokinetic variables were collected on the subjects at the end of each treatment period. Questions this study focused on refer to whether the treatments (A,B)are equivalent. A text file version of the data is found in the relation link.
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  • This dataset comes from a study on drug treatments of reflux disease patients. Twelve patients were assigned to a four period crossover design, and data on their disease symptoms were collected after treatment. Questions this study focused on refer to dosage of the drug. A text file version of the data is found in the relation link.
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  • This dataset comes from a study on pregnant rats. Forty rats were given 4 doses of a drug, and data on their fetuses were collected. Questions this study focused on refer to the relationship between dosage of the drug and gender of the fetus. A text file version of the data is found in the relation link.
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  • This dataset comes from a study on rats swimming in a T-shaped maze. Rats were given 4 doses of a drug, and their resulting pups swam the maze until they successfully escaped it 3 consecutive times. Questions from this study refer to the dosage of the drug, the number of swims until 3 consecutive successful escapes, and gender differences. A text file version of the data is found in the relation link.
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  • This dataset comes from a study on dogs 4 doses of a drug. Data on the alkaline phosphatase levels in their blood was collected throughout the experiment. Questions from this study refer to the relationship between dosage of the drug and alkaline blood levels. A text file version of the data is found in the relation link.
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  • This dataset comes from a study of 7 healthy males given a topical medication. Blood samples were collected at specified time intervals, and data on isomer concentrations were collected. Questions from this study refer to the relationship between time and concentration of the isomer. A text file version of the data is found in the relation link.
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  • This dataset comes from a study of 8 healthy males randomly assigned to a two-period crossover design, in which they either fasted and then ate, or ate and then fasted. They were given one dose of a drug, blood samples were collected and data on plasma levels were collected. Questions from this study refer to the absorption of the drug. A text file version of the data is found in the relation link.
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