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==Surrogate markers==
==Bogus statistics==
Paul Alper sent a link to the following cartoon, from the [http://statistically-funny.blogspot.com/search?updated-min=2014-01-01T00:00:00-05:00&updated-max=2015-01-01T00:00:00-05:00&max-results=3 Statistically funny] blog.
[How To Spot a Bogus Statistic]<br>
by Geoffrey James, Inc.com, 30 May 2015


::[[File:Biomarkers-Unlimited.jpg | 400px]]
The article begins by citing Bill Gates recent [http://www.gatesnotes.com/About-Bill-Gates/6-Books-I-Recommended-for-TED-2015 recommendation] that everyone should read the Darrell Huff classic ''How to Lie With Statistics''.


There is actually a serious discussion here, and the accompanying text cites [http://www.thelancet.com/journals/laninf/article/PIIS1473-3099%2814%2970896-5/abstract viral load] in HIV studies as an important example.  However,
As an object lesson, James considers efforts to dispute the scientific consensus on anthropogenic climate change.  
<blockquote>
There is a lot of controversy about surrogate outcomes - and debates about what's needed to show that an outcome or measure is a [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287814/ valid surrogate] we can rely on. They can lead us to think that a treatment is
[http://www.ncbi.nlm.nih.gov/pubmed/23360719 more effective] than it really is.
<br><br>
Yet [http://www.medpagetoday.com/PublicHealthPolicy/FDAGeneral/48244 a recent investigative report] found that cancer drugs are being increasingly approved based only on surrogate outcomes,
like "progression-free survival." That measures biomarker activity rather than overall survival (when people died).
</blockquote>


Or, quoting Paul on his favorite surrogate marker:  "If your car's dashboard light goes on, covering it up with duct tape solves the problem immediately but the car dies at the same time as if you had done nothing."
 
Submitted by Bill Peterson


==Expected value in the NFL==
==Expected value in the NFL==

Revision as of 20:59, 15 July 2015

Bogus statistics

[How To Spot a Bogus Statistic]
by Geoffrey James, Inc.com, 30 May 2015

The article begins by citing Bill Gates recent recommendation that everyone should read the Darrell Huff classic How to Lie With Statistics.

As an object lesson, James considers efforts to dispute the scientific consensus on anthropogenic climate change.


Submitted by Bill Peterson

Expected value in the NFL

Mike Olinick sent a link to the following:

N.F.L.explores making the 2-point conversion more tempting
by Victor Mather, New York Times, 19 May 2015

As football fans know, following a touchdown, the ball is placed at the two-yard line, where a team has the option of either attempting a 1-point kick or a 2-point play from scrimmage. The kick is almost a guaranteed point; last year, the overall success rate was 99.3% (1222 out of 1230). The 2-point option was introduced 20 years ago to add excitement to the game, but teams elect to use this option only about 5% of the time. The success rate for the 2-point play over this period is 47.5%, compared with 99% for the kick. An easy expected value calculation gives 0.95 points for the 2-point play compared with 0.99 points for the kick.

As announced here, the NFL decided to move the kick to the 15-yard line

Discussion

Maybe the "hot hand" exists after all

Kevin Tenenbaum sent a link to the following working paper :

Surprised by the gambler’s and hot hand fallacies? A truth in the law of small numbers
by Joshua Miller and Adam Sanjurjo, Social Science Research Network, 6 July 2015

In the abstract we read, "We find a subtle but substantial bias in a standard measure of the conditional dependence of present outcomes on streaks of past outcomes in sequential data. The mechanism is driven by a form of selection bias, which leads to an underestimate of the true conditional probability of a given outcome when conditioning on prior outcomes of the same kind." The authors give the following simple example to illustrate the bias

Jack takes a coin from his pocket and decides that he will flip it 4 times in a row, writing down the outcome of each flip on a scrap of paper. After he is done flipping, he will look at the flips that immediately followed an outcome of heads, and compute the relative frequency of heads on those flips. Because the coin is fair, Jack of course expects this conditional relative frequency to be equal to the probability of flipping a heads: 0.5. Shockingly, Jack is wrong. If he were to sample 1 million fair coins and flip each coin 4 times, observing the conditional relative frequency for each coin, on average the relative frequency would be approximately 0.4.

In Hey—guess what? There really is a hot hand! (9 July 2015), Andrew Gelman implements a simple R simulation that verifies this result (thanks to Jeff Witmer at Isostat for providing a link to this blog post).

(See also The hot hand revisited in Chance News 101 for some earlier data analyses asserting evidence for the hot hand phenomenon.)

Some math doodles

<math>P \left({A_1 \cup A_2}\right) = P\left({A_1}\right) + P\left({A_2}\right) -P \left({A_1 \cap A_2}\right)</math>


Accidental insights

My collective understanding of Power Laws would fit beneath the shallow end of the long tail. Curiosity, however, easily fills the fat end. I long have been intrigued by the concept and the surprisingly common appearance of power laws in varied natural, social and organizational dynamics. But, am I just seeing a statistical novelty or is there meaning and utility in Power Law relationships? Here’s a case in point.

While carrying a pair of 10 lb. hand weights one, by chance, slipped from my grasp and fell onto a piece of ceramic tile I had left on the carpeted floor. The fractured tile was inconsequential, meant for the trash.

BrokenTile.jpg

As I stared, slightly annoyed, at the mess, a favorite maxim of the Greek philosopher, Epictetus, came to mind: “On the occasion of every accident that befalls you, turn to yourself and ask what power you have to put it to use.” Could this array of large and small polygons form a Power Law? With curiosity piqued, I collected all the fragments and measured the area of each piece.

Piece Sq. Inches % of Total
1 43.25 31.9%
2 35.25 26.0%
3 23.25 17.2%
4 14.10 10.4%
5 7.10 5.2%
6 4.70 3.5%
7 3.60 2.7%
8 3.03 2.2%
9 0.66 0.5%
10 0.61 0.5%
Montante plot1.png

The data and plot look like a Power Law distribution. The first plot is an exponential fit of percent total area. The second plot is same data on a log normal format. Clue: Ok, data fits a straight line. I found myself again in the shallow end of the knowledge curve. Does the data reflect a Power Law or something else, and if it does what does it reflect? What insights can I gain from this accident? Favorite maxims of Epictetus and Pasteur echoed in my head: “On the occasion of every accident that befalls you, remember to turn to yourself and inquire what power you have to turn it to use” and “Chance favors only the prepared mind.”

Montante plot2.png

My “prepared” mind searched for answers, leading me down varied learning paths. Tapping the power of networks, I dropped a note to Chance News editor Bill Peterson. His quick web search surfaced a story from Nature News on research by Hans Herrmann, et. al. Shattered eggs reveal secrets of explosions. As described there, researchers have found power-law relationships for the fragments produced by shattering a pane of glass or breaking a solid object, such as a stone. Seems there is a science underpinning how things break and explode; potentially useful in Forensic reconstructions. Bill also provided a link to a vignette from CRAN describing a maximum likelihood procedure for fitting a Power Law relationship. I am now learning my way through that.

Submitted by William Montante


The p-value ban

http://www.statslife.org.uk/opinion/2114-journal-s-ban-on-null-hypothesis-significance-testing-reactions-from-the-statistical-arena