Chance News 16: Difference between revisions

From ChanceWiki
Jump to navigation Jump to search
Line 75: Line 75:


==Does a glass of wine a day keep the doctor away?==
==Does a glass of wine a day keep the doctor away?==
[http://www.sfgate.com/cgi-bin/article.cgi?file=/c/a/2006/03/30/MNGMTI0B3U1.DTL UCSF points out flaw in studies tying alcohol to heart health]<br>
San Francisco Chronicle, March 30, 2006<br>
Sabine Russell
[http://www.journalsonline.tandf.co.uk/link.asp?id=m350jp7v218202g8 Moderate alcohol use and reduced mortality risk: Systematic error in prospective studies]


A large numbers of observational studies suggest that moderate drinkers have a lower risk for heart attacks than nondrinkers or hearvy drinkers.  The results of these studies are usually illostrated by a U shaped graphic like the following:
A large numbers of observational studies suggest that moderate drinkers have a lower risk for heart attacks than nondrinkers or hearvy drinkers.  The results of these studies are usually illostrated by a U shaped graphic like the following:

Revision as of 20:40, 13 April 2006

Quotation

It is as useless to debate whether an actual sequence of coin tossing was governed by the laws of probability as "to debate the table manners of children with six arms."

Joe Doob
Chances are, Michael Kaplan and Ellen Kaplan

Here's more from Doob on this subject:

Then and later the most embarrassing probability class lecture was the first, in which I tried to give a satisfying account of what happens when one tosses a coin. (A famous statistician told me that he solves the difficulty by never mentioning the context.) One wants to talk about a limit of a frequency, but "limit" has no meaning unless an infinite sequence is involved, and an infinite sequence is not an empirical concept. I made vague and heavily hedged remarks such as that the ratio I would like to have limit l/2 "seems to tend to 1/2", that the coin tosser "would be very much surprised if the ratio is not nearly 1/2 after a large number of tosses", and so on.

The students never seemed to be bothered by my vagueness. For that matter professionals who write about the subject are usually also unbothered, perhaps because they never seem to be tossing real coins in a real world under the influence of Newton's laws, which somehow are not mentioned in the writing.

A conversation with Joe Doob
Statist. Sci. 12, no. 4 (1997), 301–311

Submitted by Laurie Snell

Forsooth

Add forsooth item here

Add source here

Exponential decay in Biblical ages

WHY did people live longer BEFORE Noah's Flood than they did after it? written by Arnold C. Mendez, Sr. and published at BibleStudy.org.

While looking on the web for good examples of the coefficient of determination, I came across a statistical analysis of the ages of Biblical patriachs. Apparently the author believes in a literal interpretation of the Bible and wants to answer skeptical comments about the unusual ages reported for some of the patriarchs in the Bible.

"One of the most intriguing facts in the Bible is the immense life spans of the patriarchs before and just after the flood. Adam lived 930 years, Methuselah the longest lived of the patriarchs lived 969 years. Noah lived 950 years."

Why is it that no one today lives so long?

"After the flood the earth was completely different than the earth before. There were widespread global differences. These would include changes in the climate, composition of the atmosphere, hydrologic cycle, geologic features, cosmic radiation reaching the earth, ozone concentration, ultra violet light, background radiation, genetics, diet, and a host of other subtle and/or profound chemical and physiological changes. These changes caused a rapid decline of the longevity of post flood humanity."

The statistical model comes in the analysis of the decline in ages after the flood. An exponential decay model produces the following equation y=487.78exp(-0.0907x) where x represents the generation number. After 20 generations, the ages settles down to a more modern figure of 70 years. The coefficient of determination is 0.889.

"This means that the decay rate of the patriarch's death after the flood was only 11% from being a perfect match."

You can view a graph of the data and the fitted line below, taken directly from the article.

http://www.biblestudy.org/basicart/longflod.gif

The author argues that the ages must be genuine since they fit an exponential curve so well and the writers of the time would not have the mathematical sophistication to fake an exponential decay curve.

Questions

1. Does a coefficient of determination of 89% sound impressive to you? What do you think about the author's comment that this is "only 11% from being a perfect match"?

2. What other models (linear or non-linear) would be worth considering for this data?

3. Is there an alternative explanation for this pattern of ages?

Submitted by Steve Simon


Is Jerry Falwell's debate team really number 1 in the nation?

Adapted from Who's Counting: Distrusting Atheists

The NY Times Magazine, Newsweek, and 60 Minutes are three of the media outlets devoting considerable attention to the "national champion" debate team from conservative fundamentalist Jerry Falwell's Liberty University. But does the team deserve this number one ranking or is it bogus, an artifact of the way the so-called overall category

As bloggers Jim Hanas, Ed Brayton and others have observed (and as is briefly and unobtrusively buried in the Times article itself), the ranking is based on the performance of the team in all tournaments, including novice and junior varsity contests.

The way rankings are determined in the "overall" category, winning at any of these second-tier tournaments adds to the team's point total. Liberty, which has a broad-based program, enters many of them and racks up many of its points by doing so.

The schools with the top individual teams, however, often don't have novice or JV teams and usually don't enter many of the lesser tournaments.

Even with such extensive, but light opposition, and the points resulting from it, the Liberty varsity team seldom reaches the semifinals and has yet to win a single varsity tournament.

In fact, in the varsity rankings Liberty is 20th, not first, and, when the quality of its opponents is taken into account, it ranks even lower than that.

As Hanas remarks, referring to Liberty as the No. 1 team and one of the nation's great collegiate debate programs is a bit "like calling the best Division III basketball team the NCAA champion."

Another analogy is to the brief 1992 presidential campaign of Iowa Sen. Tom Harkin. He was way behind in the primaries, but some of his staffers jokingly suggested that their man was leading. In winning Minnesota, Iowa and Montana, they argued that he had captured the largest land mass of any of the contenders.

Submitted by John A. Paulos

Does a glass of wine a day keep the doctor away?

UCSF points out flaw in studies tying alcohol to heart health
San Francisco Chronicle, March 30, 2006
Sabine Russell

Moderate alcohol use and reduced mortality risk: Systematic error in prospective studies


A large numbers of observational studies suggest that moderate drinkers have a lower risk for heart attacks than nondrinkers or hearvy drinkers. The results of these studies are usually illostrated by a U shaped graphic like the following:

Wine1.jpg

This graphic appears in the article "Alcohol and Mortality in British Men; Explaining the U-Shaped Curve", The Lancet, 3 December 1988, A. Shaper, Goya Wannamethee, and Mary Walker. In their summary the authors write:

In a propective study of 7735 middle-aged British men, 504 of whom died in a follow-up period of 7.5 years, there was a U-shaped relationship between alcohol intake and total mortality and an inverse relationship with cardiovascular mortality, even after adjustment for age, cigarette smoking, and social class. These mortality patterns were seen in all smoking categories (with ex-smoking non-drinkers having the highest mortalilty) and were observed in manual but not in non-manual workers. The alcohol-mortality relationships are produced by pre-existing disease and by the movement of men with such disease into non-drinking or occasional-drinking categories. The concept of a "protective"effect of drinking on mortality, ingnoring the dynamic relationsip between ill-health and drinking behavior, is likely to be ill founded.

The authors are concerned that this and other studies are seriously flawed because the include subjects who have recently quit smoking who are typically older people who have had medical problems and told be their doctors to quit drinking. They are suggesting that this could explain why those who drink are less likely to have a higher mortallity rate than moderate drinkers.

This concern was evidently not followed up until a recent study




Two recent studies suggest that these studies are seriously flawed. The first was a study was a study by the Centers for Disease Control and published in the American Journal of Preventive Medicine Volume 28, Issue 4 , May 2005, Pages 369-373. The results of this study are reported as follows:

Background

Studies suggest that moderate drinkers have lower cardiovascular disease (CVD) mortality than nondrinkers and heavy drinkers, but there have been no randomized trials on this topic. Although most observational studies control for major cardiac risk factors, CVD is independently associated with other factors that could explain the CVD benefits ascribed to moderate drinking.

Methods

Data from the 2003 Behavioral Risk Factor Surveillance System, a population-based telephone survey of U.S. adults, was used to assess the prevalence of CVD risk factors and potential confounders among moderate drinkers and nondrinkers. Moderate drinkers were defined as men who drank an average of two drinks per day or fewer, or women who drank one drink or fewer per day.

Results

After adjusting for age and gender, nondrinkers were more likely to have characteristics associated with increased CVD mortality in terms of demographic factors, social factors, behavioral factors, access to health care, and health-related conditions. Of the 30 CVD-associated factors or groups of factors that we assessed, 27 (90%) were significantly more prevalent among nondrinkers. Among factors with multiple categories (e.g., body weight), those in higher-risk groups were progressively more likely to be nondrinkers. Removing those with poor health status or a history of CVD did not affect the results.

Conclusions

These findings suggest that some or all of the apparent protective effect of moderate alcohol consumption on CVD may be due to residual or unmeasured confounding. Given their limitations, nonrandomized studies about the health effects of moderate drinking should be interpreted with caution, particularly since excessive alcohol consumption is a leading health hazard in the United States.

To be continued: